=> Bootstrap dependency digest>=20211023: found digest-20220214
ERROR: This package is only available for these platforms: *-*-x86_64 *-*-aarch64.
ERROR: This package has set PKG_SKIP_REASON:
ERROR: hisat2-2.2.1nb4 is not available for NetBSD-10.0-alpha
*** Error code 1

Stop.
make: stopped in /usr/pkgsrc/biology/hisat2